2-Amino-3-hydroxy-4-bromopyridine hydrobromide - Names and Identifiers
2-Amino-3-hydroxy-4-bromopyridine hydrobromide - Physico-chemical Properties
Molecular Formula | C5H6Br2N2O
|
Molar Mass | 269.92194 |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
2-Amino-3-hydroxy-4-bromopyridine hydrobromide - Introduction
2-amino -3-hydroxy -4-bromopyridine hydrogen bromide, chemical formula is C5H5Br2N2O.
Nature:
1. Appearance: White crystalline solid.
2. melting point: about 165 ℃.
3. stability: sensitive to light and air, should be stored in the dark, dry, sealed conditions.
Use:
1. 2-Amino-3-hydroxy-4-bromopyridine hydrogen bromide is an important pharmaceutical intermediate, which is widely used in organic synthesis and pharmaceutical industry.
2. it can be used for the synthesis of lodilol, ezonapril and other drugs.
Method:
2-amino -3-hydroxy -4-bromine pyridine hydrogen bromide preparation method is more, the following is a commonly used preparation method:
2-amino -3-bromopyridine is generated by reacting 2-bromopyridine with ammonium hydroxide, and then 2-amino -3-hydroxy -4-bromopyridine is obtained by alternately treating with sodium hydroxide and potassium hydroxide. Finally, 2-amino-3-hydroxy-4-bromopyridine hydrogen bromide is obtained by reaction with hydrochloric acid.
Safety Information:
1. 2-Amino-3-hydroxy-4-bromopyridine hydrogen bromide has certain irritation and corrosiveness to eyes. It is necessary to prevent contact with skin and eyes when using it.
2. Wear appropriate personal protective equipment such as lab gloves and goggles during operation.
3. in the process of storage and handling to avoid high temperature, fire and open flame.
Last Update:2024-04-09 21:00:56